Effectiveness of Intratympanic Dexamethasone with Lidocaine for Alleviation of Tinnitus

Objective: To determine the effectiveness of Intratympanic Dexamethasone with Lidocaine in control idiopathic tinnitus.
 Study Design: Randomized trial (Clinical Trials. gov Identifier: NCT04798391).
 Place and Duration Study: ENT Department, PAF Hospital, Sargodha Pakistan, from Apr 2017 to Jul 2019.
 Methodology: 264 consenting patients unilateral tinnitus presenting at Department Hospital were assessed for severity using modified handicap inventory. The scores recorded subsequently administered intra-tympanicaly 2.0ml (milli-liter) (1.5 ml ± 0.5 1% Lidocaine). dose was repeated twice weekly intervals. All reassessed on inventory two weeks after third Intra-tympanic administration, divided into responsive noresponsive groups depending ten points or more improvement score.
 Results: Mean score pre-therapy 29.6 5.68, post-therapy 17.1 7.45. Independent-sample T-test applied showed a p-value <0.001.
 Conclusion: lidocaine has definitively positive outcome improvement.